4 'should-win' Matchups For Arizona Cardinals In 2025

The Arizona Cardinals and the rest of the NFL will know their 2025 regular-season schedules on Wednesday. The official schedule release begins at 5 p.m. Arizona time.
We don't know any of the Cardinals' specific games, but we do know all their 2025 opponents.
2025 Arizona Cardinals opponents
Home opponents
- Los Angeles Rams (division game)
- San Francisco 49ers (division game)
- Seattle Seahawks (division game)
- Atlanta Falcons (NFC South game)
- Carolina Panthers (NFC South game)
- Jacksonville Jaguars (AFC South game)
- Tennessee Titans (AFC South game)
- Green Bay Packers (third-place conference game)
Road opponents
- Los Angeles Rams (division game)
- San Francisco 49ers (division game)
- Seattle Seahawks (division game)
- New Orleans Saints (NFC South game)
- Tampa Bay Buccaneers (NFC South game)
- Houston Texans (AFC South game)
- Indianapolis Colts (AFC South game)
- Dallas Cowboys (third-place conference game)
- Cincinnati Bengals (third-place AFC team for 17th game)
Of those opponents, four qualify as games the Cardinals simply should win. They are teams who should be considered worse than they are. Last season, the Cardinals were very good about beating the teams they "should" beat, with the exception of their late-season loss to the Carolina Panthers.
Which four games are the "should-win" games?
4 games the Cardinals should win
- Carolina Panthers (home): The Cardinals should have beaten the Panthers last season, and that loss was what essentially ended their playoff hopes. Both teams have made improvements, but if the Cardinals have real postseason aspirations, this is a game they should win.
- Jacksonville Jaguars (home): They have a new head coach and are coming off a bad year.
- Tennessee Titans (home): The Titans were a disaster last season and now have a rookie quarterback.
- Indianapolis Colts (away): Their quarterback situation makes them a team the Cardinals have to take advantage of.
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This article originally appeared on Cards Wire: NFL schedule: 4 'should-win' games for the Arizona Cardinals